BindingDB PrimarySearch

Found 2 hits Enz. Inhib. hit(s) with Target = 'Histamine H3 receptor' and Ligand = 'BDBM50237872'
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Histamine H3 receptor (Homo sapiens (Human))	BDBM50237872 (2-(3-(2-((R)-2-methylpyrrolidin-1-yl)ethyl)-1-(2-(...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.470	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Kyowa Hakko Kogyo Co. Ltd Curated by ChEMBL					Assay Description Displacement of [3H]N-alpha-methylhistamine from human cloned histamine H3 receptor expressed in monkey COS7 cells				Bioorg Med Chem Lett 18: 2288-91 (2008) Article DOI: 10.1016/j.bmcl.2008.03.006 BindingDB Entry DOI: 10.7270/Q2KW5FSF
Kyowa Hakko Kogyo Co. Ltd Curated by ChEMBL					More data for this Ligand-Target Pair
Histamine H3 receptor (Rattus norvegicus (rat))	BDBM50237872 (2-(3-(2-((R)-2-methylpyrrolidin-1-yl)ethyl)-1-(2-(...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.770	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Kyowa Hakko Kogyo Co. Ltd Curated by ChEMBL					Assay Description Displacement of [3H]N-alpha-methylhistamine from histamine H3 receptor in rat striatal membrane				Bioorg Med Chem Lett 18: 2288-91 (2008) Article DOI: 10.1016/j.bmcl.2008.03.006 BindingDB Entry DOI: 10.7270/Q2KW5FSF
Kyowa Hakko Kogyo Co. Ltd Curated by ChEMBL					More data for this Ligand-Target Pair