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Found 1 hit Enz. Inhib. hit(s) with Target = 'Histamine H3 receptor' and Ligand = 'BDBM50265094'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Histamine H3 receptor


(Homo sapiens (Human))		BDBM50265094
PNG
(2-(ethylthio)-5-fluoro-1-(4-(3-(piperidin-1-yl)pro...)
Show SMILES CCSC1Nc2cc(F)ccc2N1c1ccc(OCCCN2CCCCC2)cc1
Show InChI InChI=1S/C23H30FN3OS/c1-2-29-23-25-21-17-18(24)7-12-22(21)27(23)19-8-10-20(11-9-19)28-16-6-15-26-13-4-3-5-14-26/h7-12,17,23,25H,2-6,13-16H2,1H3
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Article
PubMed
 2.60n/an/an/an/an/an/an/an/a



The Schering Plough Research Institute

Curated by ChEMBL


Assay Description
Displacement of [3H]N-alpha-methylhistamine from human histamine H3 receptor expressed in HEK cells by scintillation counting

Bioorg Med Chem Lett 18: 5032-6 (2008)


Article DOI: 10.1016/j.bmcl.2008.08.008
BindingDB Entry DOI: 10.7270/Q2CZ370Q
More data for this
Ligand-Target Pair