Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Histamine H3 receptor' and Ligand = 'BDBM50297369'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histamine H3 receptor (Rattus norvegicus (rat))	BDBM50297369 (4'-[2-((R)-2-Methyl-pyrrolidin-1-yl)-ethyl]-biphen...) Show SMILES COCCNS(=O)(=O)c1ccc(cc1)-c1ccc(CCN2CCC[C@H]2C)cc1 |r| Show InChI InChI=1S/C22H30N2O3S/c1-18-4-3-15-24(18)16-13-19-5-7-20(8-6-19)21-9-11-22(12-10-21)28(25,26)23-14-17-27-2/h5-12,18,23H,3-4,13-17H2,1-2H3/t18-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Arena Pharmaceuticals Curated by ChEMBL					Assay Description Displacement of N-[3H]methylhistamine from histamine H3 receptor in rat cortex membrane				J Med Chem 52: 5603-11 (2009) Article DOI: 10.1021/jm900857n BindingDB Entry DOI: 10.7270/Q2KW5G2F
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50297369 (4'-[2-((R)-2-Methyl-pyrrolidin-1-yl)-ethyl]-biphen...) Show SMILES COCCNS(=O)(=O)c1ccc(cc1)-c1ccc(CCN2CCC[C@H]2C)cc1 |r| Show InChI InChI=1S/C22H30N2O3S/c1-18-4-3-15-24(18)16-13-19-5-7-20(8-6-19)21-9-11-22(12-10-21)28(25,26)23-14-17-27-2/h5-12,18,23H,3-4,13-17H2,1-2H3/t18-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Bioprojet-Biotech Curated by ChEMBL					Assay Description Displacement of [125I]Iodoproxyfan from human recombinant histamine H3 receptor by Competitive binding assay				Bioorg Med Chem Lett 21: 5378-83 (2011) Article DOI: 10.1016/j.bmcl.2011.07.006 BindingDB Entry DOI: 10.7270/Q2VX0GXK
					More data for this Ligand-Target Pair