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Found 1 hit Enz. Inhib. hit(s) with Target = 'Histamine H3 receptor' and Ligand = 'BDBM50325452'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Histamine H3 receptor


(GUINEA PIG)		BDBM50325452
PNG
(1-(1-(1-(quinolin-4-ylmethyl)piperidine-4-carbonyl...)
Show SMILES O=C(C1CCN(Cc2ccnc3ccccc23)CC1)N1CCC(CC1)n1c2ccccc2[nH]c1=O
Show InChI InChI=1S/C28H31N5O2/c34-27(32-17-12-22(13-18-32)33-26-8-4-3-7-25(26)30-28(33)35)20-10-15-31(16-11-20)19-21-9-14-29-24-6-2-1-5-23(21)24/h1-9,14,20,22H,10-13,15-19H2,(H,30,35)
PDB

UniProtKB/SwissProt

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CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
 681n/an/an/an/an/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
Displacement of [3H]Nalpha-methylhistamine from histamine H3 receptor in guinea pig brain

Bioorg Med Chem Lett 20: 5004-8 (2010)


Article DOI: 10.1016/j.bmcl.2010.07.052
BindingDB Entry DOI: 10.7270/Q2N016QS
More data for this
Ligand-Target Pair