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Found 1 hit Enz. Inhib. hit(s) with Target = 'Histamine H3 receptor' and Ligand = 'BDBM50325484'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Histamine H3 receptor


(GUINEA PIG)		BDBM50325484
PNG
((4-phenylpiperazin-1-yl)(1-(pyridin-4-ylmethyl)pip...)
Show SMILES O=C(C1CCN(Cc2ccncc2)CC1)N1CCN(CC1)c1ccccc1
Show InChI InChI=1S/C22H28N4O/c27-22(26-16-14-25(15-17-26)21-4-2-1-3-5-21)20-8-12-24(13-9-20)18-19-6-10-23-11-7-19/h1-7,10-11,20H,8-9,12-18H2
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
 40n/an/an/an/an/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
Displacement of [3H]Nalpha-methylhistamine from histamine H3 receptor in guinea pig brain

Bioorg Med Chem Lett 20: 5004-8 (2010)


Article DOI: 10.1016/j.bmcl.2010.07.052
BindingDB Entry DOI: 10.7270/Q2N016QS
More data for this
Ligand-Target Pair