Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Histamine H3 receptor (Homo sapiens (Human)) | BDBM50384401 (CHEMBL2031470) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 3.60 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Cephalon, Inc. Curated by ChEMBL | Assay Description Displacement of [3H]NAMH from human histamine H3 receptor expressed in CHO cell membrane | Bioorg Med Chem Lett 22: 4198-202 (2012) Article DOI: 10.1016/j.bmcl.2012.04.001 BindingDB Entry DOI: 10.7270/Q2QR4Z52 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Histamine H3 receptor (Rattus norvegicus (rat)) | BDBM50384401 (CHEMBL2031470) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 8.30 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Cephalon, Inc. Curated by ChEMBL | Assay Description Displacement of [3H]NAMH from rat histamine H3 receptor expressed in CHO cell membrane | Bioorg Med Chem Lett 22: 4198-202 (2012) Article DOI: 10.1016/j.bmcl.2012.04.001 BindingDB Entry DOI: 10.7270/Q2QR4Z52 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Histamine H3 receptor (Homo sapiens (Human)) | BDBM50384401 (CHEMBL2031470) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 1.70 | n/a | n/a | n/a | n/a |
Cephalon, Inc. Curated by ChEMBL | Assay Description Inverse agonist activity at human H3 receptor by [35S]GTPgamma binding assay | Bioorg Med Chem Lett 22: 4198-202 (2012) Article DOI: 10.1016/j.bmcl.2012.04.001 BindingDB Entry DOI: 10.7270/Q2QR4Z52 | |||||||||||
More data for this Ligand-Target Pair |