BindingDB logo
myBDB logout
Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Histamine H3 receptor' and Ligand = 'BDBM50517506'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Histamine H3 receptor


(Homo sapiens (Human))		BDBM50517506
PNG
(CHEMBL4476420)
Show SMILES Cl.Cl.Cc1cc(OC2CCN(CC2)C2CCC2)ccc1NC(=O)CN1CCCCC1
Show InChI InChI=1S/C23H35N3O2/c1-18-16-21(28-20-10-14-26(15-11-20)19-6-5-7-19)8-9-22(18)24-23(27)17-25-12-3-2-4-13-25/h8-9,16,19-20H,2-7,10-15,17H2,1H3,(H,24,27)
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
 3.30n/an/an/an/an/an/an/an/a



Suven Life Sciences Ltd

Curated by ChEMBL


Assay Description
Displacement of [3]-RAMH from recombinant human histamine H3 receptor expressed in CHO-K1 cell membranes after 60 mins by scintillation counting

J Med Chem 62: 1203-1217 (2019)


Article DOI: 10.1021/acs.jmedchem.8b01280
BindingDB Entry DOI: 10.7270/Q2XD152G
More data for this
Ligand-Target Pair