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Found 1 hit Enz. Inhib. hit(s) with Target = 'Histamine H3 receptor' and Ligand = 'BDBM50517529'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Histamine H3 receptor


(Homo sapiens (Human))		BDBM50517529
PNG
(CHEMBL4587541)
Show SMILES Cl.Cl.OCC1CCCN1CC(=O)Nc1ccc(OC2CCN(CC2)C2CCC2)cc1
Show InChI InChI=1S/C22H33N3O3.2ClH/c26-16-19-5-2-12-25(19)15-22(27)23-17-6-8-20(9-7-17)28-21-10-13-24(14-11-21)18-3-1-4-18;;/h6-9,18-19,21,26H,1-5,10-16H2,(H,23,27);2*1H
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Article
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 1.20n/an/an/an/an/an/an/an/a



Suven Life Sciences Ltd

Curated by ChEMBL


Assay Description
Displacement of [3]-RAMH from recombinant human histamine H3 receptor expressed in CHO-K1 cell membranes after 60 mins by scintillation counting

J Med Chem 62: 1203-1217 (2019)


Article DOI: 10.1021/acs.jmedchem.8b01280
BindingDB Entry DOI: 10.7270/Q2XD152G
More data for this
Ligand-Target Pair