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Found 1 hit Enz. Inhib. hit(s) with Target = 'Histamine H3 receptor' and Ligand = 'BDBM50517531'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Histamine H3 receptor


(Homo sapiens (Human))		BDBM50517531
PNG
(CHEMBL4445638)
Show SMILES Cl.Cl.O=C(CN1CCCC1)Nc1ccc(OC2CCN(CC2)C2CCC2)cc1
Show InChI InChI=1S/C21H31N3O2/c25-21(16-23-12-1-2-13-23)22-17-6-8-19(9-7-17)26-20-10-14-24(15-11-20)18-4-3-5-18/h6-9,18,20H,1-5,10-16H2,(H,22,25)
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PC cid
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Article
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 1.10n/an/an/an/an/an/an/an/a



Suven Life Sciences Ltd

Curated by ChEMBL


Assay Description
Displacement of [3]-RAMH from recombinant human histamine H3 receptor expressed in CHO-K1 cell membranes after 60 mins by scintillation counting

J Med Chem 62: 1203-1217 (2019)


Article DOI: 10.1021/acs.jmedchem.8b01280
BindingDB Entry DOI: 10.7270/Q2XD152G
More data for this
Ligand-Target Pair