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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Histamine H3 receptor' and Ligand = 'BDBM50517540'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Histamine H3 receptor


(Homo sapiens (Human))
BDBM50517540
PNG
(CHEMBL4452215)
Show SMILES O=C(NCCN1CCOCC1)c1ccc(OC2CCN(CC2)C2CCC2)cc1
Show InChI InChI=1S/C22H33N3O3/c26-22(23-10-13-24-14-16-27-17-15-24)18-4-6-20(7-5-18)28-21-8-11-25(12-9-21)19-2-1-3-19/h4-7,19,21H,1-3,8-17H2,(H,23,26)
PDB

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PC cid
PC sid
UniChem
Article
PubMed
2.80n/an/an/an/an/an/an/an/a



Suven Life Sciences Ltd

Curated by ChEMBL


Assay Description
Displacement of [3]-RAMH from recombinant human histamine H3 receptor expressed in CHO-K1 cell membranes after 60 mins by scintillation counting


J Med Chem 62: 1203-1217 (2019)


Article DOI: 10.1021/acs.jmedchem.8b01280
BindingDB Entry DOI: 10.7270/Q2XD152G
More data for this
Ligand-Target Pair