Compile Data Set for Download or QSAR

Found 3 hits Enz. Inhib. hit(s) with Target = 'Histamine H4 receptor' and Ligand = 'BDBM189353'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histamine H4 receptor (Homo sapiens (Human))	BDBM189353 (4-Benzyl-6-(4-methylpiperazin-1-yl)-1,3,5-triazin-...) Show SMILES CN1CCN(CC1)c1nc(N)nc(Cc2ccccc2)n1 Show InChI InChI=1S/C15H20N6/c1-20-7-9-21(10-8-20)15-18-13(17-14(16)19-15)11-12-5-3-2-4-6-12/h2-6H,7-11H2,1H3,(H2,16,17,18,19)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	7.50E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Department of Technology and Biotechnology of Drugs, Jagiellonian University, Medical College, Medyczna 9, PL 30-688 Kraków, Poland. Electronic address: dlazewska@cm-uj.krakow.pl. Curated by ChEMBL					Assay Description Displacement of [3H]-histamine from human histamine H4R expressed in insect Sf9 cell membranes co-expressing Galphai2 and Gbeta1gamma2 after 60 mins ...				Eur J Med Chem 135: 117-124 (2017) Article DOI: 10.1016/j.ejmech.2017.04.033 BindingDB Entry DOI: 10.7270/Q2QN696C
					More data for this Ligand-Target Pair
Histamine H4 receptor (Homo sapiens (Human))	BDBM189353 (4-Benzyl-6-(4-methylpiperazin-1-yl)-1,3,5-triazin-...) Show SMILES CN1CCN(CC1)c1nc(N)nc(Cc2ccccc2)n1 Show InChI InChI=1S/C15H20N6/c1-20-7-9-21(10-8-20)15-18-13(17-14(16)19-15)11-12-5-3-2-4-6-12/h2-6H,7-11H2,1H3,(H2,16,17,18,19)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	7.50E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Palermo Curated by ChEMBL					Assay Description Displacement of [3H]histamine from human H4R expressed in Sf9 cell membranes co-expressed with G protein Gai2 and Gb1gamma2 incubated for 60 mins by ...				Eur J Med Chem 142: 523-549 (2017) Article DOI: 10.1016/j.ejmech.2017.09.035 BindingDB Entry DOI: 10.7270/Q2HH6NRF
					More data for this Ligand-Target Pair
Histamine H4 receptor (Homo sapiens (Human))	BDBM189353 (4-Benzyl-6-(4-methylpiperazin-1-yl)-1,3,5-triazin-...) Show SMILES CN1CCN(CC1)c1nc(N)nc(Cc2ccccc2)n1 Show InChI InChI=1S/C15H20N6/c1-20-7-9-21(10-8-20)15-18-13(17-14(16)19-15)11-12-5-3-2-4-6-12/h2-6H,7-11H2,1H3,(H2,16,17,18,19)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	7.50E+3	-27.2	n/a	n/a	n/a	n/a	n/a	7.4	4
Jagiellonian University Medical College					Assay Description Prior to the experiments, cell membranes were sedimented by a 10 min centrifugation at 4 °C and 16 0009x g and resuspended in binding buffer (12...				Chem Biol Drug Des 88: 254-63 (2016) Article DOI: 10.1111/cbdd.12752 BindingDB Entry DOI: 10.7270/Q21R6P93
					More data for this Ligand-Target Pair