Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Histamine H4 receptor' and Ligand = 'BDBM315391'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histamine H4 receptor (Homo sapiens (Human))	BDBM315391 (US10172856, Example 43) Show SMILES CCN(c1ccnc(N)n1)c1ccc(cc1C1CCC1)S(=O)(=O)C(F)(F)F Show InChI InChI=1S/C17H19F3N4O2S/c1-2-24(15-8-9-22-16(21)23-15)14-7-6-12(27(25,26)17(18,19)20)10-13(14)11-4-3-5-11/h6-11H,2-5H2,1H3,(H2,21,22,23)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	8	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Pharmaceutica NV US Patent					Assay Description Receptor binding was assessed using isolated plasma membranes from SKNMC neuroblastoma cell lines stably expressing recombinant human H4 receptor. To...				US Patent US10172856 (2019) BindingDB Entry DOI: 10.7270/Q2BV7JQ1
					More data for this Ligand-Target Pair