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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Histamine H4 receptor' and Ligand = 'BDBM50319297'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Histamine H4 receptor


(Homo sapiens (Human))
BDBM50319297
PNG
(5-fluoro-4-methyl-2-(2-methyl-4-(5-(pyridin-3-yl)p...)
Show SMILES Cc1cc(OCCCCCc2cccnc2)ccc1-c1nc2ccc(F)c(C)c2[nH]1
Show InChI InChI=1S/C25H26FN3O/c1-17-15-20(30-14-5-3-4-7-19-8-6-13-27-16-19)9-10-21(17)25-28-23-12-11-22(26)18(2)24(23)29-25/h6,8-13,15-16H,3-5,7,14H2,1-2H3,(H,28,29)
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PC cid
PC sid
UniChem
Article
PubMed
152n/an/an/an/an/an/an/an/a



Johnson& Johnson Pharmaceutical Research& Development

Curated by ChEMBL


Assay Description
Displacement of [3H]histamine from human recombinant histamine H4 receptor


Bioorg Med Chem Lett 20: 3367-71 (2010)


Article DOI: 10.1016/j.bmcl.2010.04.017
BindingDB Entry DOI: 10.7270/Q23J3D4Z
More data for this
Ligand-Target Pair