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Found 1 hit Enz. Inhib. hit(s) with Target = 'Histamine H4 receptor' and Ligand = 'BDBM50412485'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Histamine H4 receptor


(Homo sapiens (Human))		BDBM50412485
PNG
(CHEMBL461731)
Show SMILES CNc1nc(nc2ccc(Cl)cc12)N1CC(C)N(C)C(C)C1
Show InChI InChI=1S/C16H22ClN5/c1-10-8-22(9-11(2)21(10)4)16-19-14-6-5-12(17)7-13(14)15(18-3)20-16/h5-7,10-11H,8-9H2,1-4H3,(H,18,19,20)
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Similars
Article
PubMed
>1.00E+3n/an/an/an/an/an/an/an/a



Vrije Universiteit Amsterdam

Curated by ChEMBL


Assay Description
Displacement of [3H]histamine from human histamine H4 receptor expressed in HEK cells

J Med Chem 51: 7855-65 (2008)


Article DOI: 10.1021/jm800876b
BindingDB Entry DOI: 10.7270/Q29Z964R
More data for this
Ligand-Target Pair