BindingDB PrimarySearch

Found 2 hits Enz. Inhib. hit(s) with Target = 'Histamine H4 receptor' and Ligand = 'BDBM50419329'
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Histamine H4 receptor (Homo sapiens (Human))	BDBM50419329 (CHEMBL1910378) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	5.89E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Regensburg Curated by ChEMBL					Assay Description Displacement of [3H]histamine from human H4R expressed in Sf9 cells co-expressing RGS19, Galphai2 and Gbeta1gamma2 after 60 mins by liquid scintillat...				Bioorg Med Chem Lett 21: 6274-80 (2011) Article DOI: 10.1016/j.bmcl.2011.09.001 BindingDB Entry DOI: 10.7270/Q28K7BB7
University of Regensburg Curated by ChEMBL					More data for this Ligand-Target Pair
Histamine H4 receptor (Homo sapiens (Human))	BDBM50419329 (CHEMBL1910378) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1.05E+5	n/a	n/a	n/a	n/a
University of Regensburg Curated by ChEMBL					Assay Description Partial agonist activity at human H4R expressed in Sf9 cells co-expressing RGS19, Galphai2 and Gbeta1gamma2 assessed as stimulation of [35S]GTPgammaS...				Bioorg Med Chem Lett 21: 6274-80 (2011) Article DOI: 10.1016/j.bmcl.2011.09.001 BindingDB Entry DOI: 10.7270/Q28K7BB7
University of Regensburg Curated by ChEMBL					More data for this Ligand-Target Pair