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Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Histamine H4 receptor' and Ligand = 'BDBM50474245'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Histamine H4 receptor


(Homo sapiens (Human))
BDBM50474245
PNG
(CHEMBL320279)
Show SMILES NC[C@H]1O[C@H](C=C1)c1c[nH]cn1 |c:5|
Show InChI InChI=1S/C8H11N3O/c9-3-6-1-2-8(12-6)7-4-10-5-11-7/h1-2,4-6,8H,3,9H2,(H,10,11)/t6-,8+/m0/s1
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UniProtKB/SwissProt

DrugBank
antibodypedia
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AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
2.19E+4n/an/an/an/an/an/an/an/a



Osaka University

Curated by ChEMBL


Assay Description
Histamine H4 receptor competition binding using [3H]Na-methylhistamine


J Med Chem 46: 3162-5 (2003)


Article DOI: 10.1021/jm0300025
BindingDB Entry DOI: 10.7270/Q24B343F
More data for this
Ligand-Target Pair
Histamine H4 receptor


(Homo sapiens (Human))
BDBM50474245
PNG
(CHEMBL320279)
Show SMILES NC[C@H]1O[C@H](C=C1)c1c[nH]cn1 |c:5|
Show InChI InChI=1S/C8H11N3O/c9-3-6-1-2-8(12-6)7-4-10-5-11-7/h1-2,4-6,8H,3,9H2,(H,10,11)/t6-,8+/m0/s1
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/an/an/a 4.07E+4n/an/an/an/a



Osaka University

Curated by ChEMBL


Assay Description
Inhibition of the forskolin-stimulated cAMP production in SK-N-MC cells expressing human Histamine H4 receptor


J Med Chem 46: 3162-5 (2003)


Article DOI: 10.1021/jm0300025
BindingDB Entry DOI: 10.7270/Q24B343F
More data for this
Ligand-Target Pair