Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Histamine N-methyltransferase' and Ligand = 'BDBM50110281'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histamine N-methyltransferase (Rattus norvegicus)	BDBM50110281 (CHEMBL14656 | Methyl-(3-piperidin-1-yl-propyl)-(1,...) Show SMILES CN(CCCN1CCCCC1)c1c2CCCCc2nc2ccccc12 Show InChI InChI=1S/C22H31N3/c1-24(14-9-17-25-15-7-2-8-16-25)22-18-10-3-5-12-20(18)23-21-13-6-4-11-19(21)22/h3,5,10,12H,2,4,6-9,11,13-17H2,1H3	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	360	n/a	n/a	n/a	n/a	n/a	n/a
Freie Universität Berlin Curated by ChEMBL					Assay Description Inhibition of rat kidney Histamine N-Methyltransferase (HMT) activity determined by the formation of N-methylhistamine				J Med Chem 45: 1128-41 (2002) BindingDB Entry DOI: 10.7270/Q2H70F4V
					More data for this Ligand-Target Pair