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Found 1 hit Enz. Inhib. hit(s) with Target = 'Histamine N-methyltransferase' and Ligand = 'BDBM50110282'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Histamine N-methyltransferase


(Rattus norvegicus)		BDBM50110282
PNG
((7-Chloro-quinolin-4-yl)-(7-piperidin-1-yl-heptyl)...)
Show SMILES Clc1ccc2c(NCCCCCCCN3CCCCC3)ccnc2c1
Show InChI InChI=1S/C21H30ClN3/c22-18-9-10-19-20(11-13-24-21(19)17-18)23-12-5-2-1-3-6-14-25-15-7-4-8-16-25/h9-11,13,17H,1-8,12,14-16H2,(H,23,24)
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
PubMed
n/an/a 120n/an/an/an/an/an/a



Freie Universität Berlin

Curated by ChEMBL


Assay Description
Inhibition of rat kidney Histamine N-Methyltransferase (HMT) activity determined by the formation of N-methylhistamine

J Med Chem 45: 1128-41 (2002)


BindingDB Entry DOI: 10.7270/Q2H70F4V
More data for this
Ligand-Target Pair