Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Histone acetyltransferase KAT2B' and Ligand = 'BDBM50234928'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histone acetyltransferase KAT2B (Homo sapiens (Human))	BDBM50234928 (CHEMBL4063947 | US10239861, Example 2) Show SMILES CN1CCC(CC1)Nc1cnn(C)c(=O)c1Cl Show InChI InChI=1S/C11H17ClN4O/c1-15-5-3-8(4-6-15)14-9-7-13-16(2)11(17)10(9)12/h7-8,14H,3-6H2,1-2H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	US Patent	n/a	n/a	1.22E+3	n/a	n/a	n/a	n/a	n/a	n/a
GLSynthesis Inc.					Assay Description His/Flag epitope tagged PCAF719-832 bromodomain was cloned, expressed and purified to homogeneity in-house. PCAF bromodomain binding and inhibition o...				J Med Chem 48: 3919-29 (2005) BindingDB Entry DOI: 10.7270/Q2X06991
					More data for this Ligand-Target Pair
Histone acetyltransferase KAT2B (Homo sapiens (Human))	BDBM50234928 (CHEMBL4063947 | US10239861, Example 2) Show SMILES CN1CCC(CC1)Nc1cnn(C)c(=O)c1Cl Show InChI InChI=1S/C11H17ClN4O/c1-15-5-3-8(4-6-15)14-9-7-13-16(2)11(17)10(9)12/h7-8,14H,3-6H2,1-2H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.58E+4	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Displacement of GSK3103956A from FLAG-6 His-Halo tagged human PCAF bromodomain (715 to 831 residues) incubated for 30 mins in dark by TR-FRET assay				J Med Chem 60: 695-709 (2017) Article DOI: 10.1021/acs.jmedchem.6b01566 BindingDB Entry DOI: 10.7270/Q2W09863
					More data for this Ligand-Target Pair