Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Histone acetyltransferase KAT2B [719-832]' and Ligand = 'BDBM311474'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histone acetyltransferase KAT2B [719-832] (Homo sapiens (Human))	BDBM311474 (CHEM-US-00176 | US10155764, Example 54B) Show SMILES CN(C)[C@@H]1CCCC[C@@H]1Nc1nn(C)c(=O)c2ccccc12 |r| Show InChI InChI=1S/C17H24N4O/c1-20(2)15-11-7-6-10-14(15)18-16-12-8-4-5-9-13(12)17(22)21(3)19-16/h4-5,8-9,14-15H,6-7,10-11H2,1-3H3,(H,18,19)/t14-,15+/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.10E+4	n/a	n/a	n/a	n/a	n/a	n/a
GENENTECH, INC; CONSTELLATION PHARMACEUTICALS, INC. US Patent					Assay Description His/Flag epitope tagged PCAF719-832 bromodomain was cloned, expressed and purified to homogeneity in-house. PCAF bromodomain binding and inhibition o...				US Patent US10155764 (2018) BindingDB Entry DOI: 10.7270/Q25M67T9
					More data for this Ligand-Target Pair