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Found 1 hit Enz. Inhib. hit(s) with Target = 'Histone acetyltransferase KAT6A [507-778]' and Ligand = 'BDBM50527264'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Histone acetyltransferase KAT6A [507-778]


(Homo sapiens)		BDBM50527264
PNG
(CHEMBL4530056)
Show SMILES CCOCc1cc(C)cc(c1)C(=O)NNS(=O)(=O)c1ccccc1F
Show InChI InChI=1S/C17H19FN2O4S/c1-3-24-11-13-8-12(2)9-14(10-13)17(21)19-20-25(22,23)16-7-5-4-6-15(16)18/h4-10,20H,3,11H2,1-2H3,(H,19,21)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 24n/an/an/an/an/an/a



Monash University (Parkville Campus)

Curated by ChEMBL


Assay Description
Inhibition of N-terminal NusA-fused His6-tagged human KAT6A (507 to 778 residues) expressed in Escherichia coli BL21 (DE3) cells using 0.4 uM acetyl ...

J Med Chem 63: 4655-4684 (2020)


Article DOI: 10.1021/acs.jmedchem.9b02071
BindingDB Entry DOI: 10.7270/Q2W66Q7V
More data for this
Ligand-Target Pair