Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Histone chaperone ASF1A' and Ligand = 'BDBM50101682'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histone chaperone ASF1A (Homo sapiens (Human))	BDBM50101682 (CHEMBL3394916) Show SMILES O=C(N\N=C\c1cccc(OCCN2CCOCC2)c1)c1ccc(NC(=O)c2ccccc2)cc1 Show InChI InChI=1S/C27H28N4O4/c32-26(22-6-2-1-3-7-22)29-24-11-9-23(10-12-24)27(33)30-28-20-21-5-4-8-25(19-21)35-18-15-31-13-16-34-17-14-31/h1-12,19-20H,13-18H2,(H,29,32)(H,30,33)/b28-20+	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Colorado State University Curated by ChEMBL					Assay Description Inhibition of His-tagged human Asf1a binding with H3/H4 assessed as fluorescence intensity after 30 mins by ALPHA assay				Bioorg Med Chem Lett 25: 963-8 (2015) Article DOI: 10.1016/j.bmcl.2014.11.067 BindingDB Entry DOI: 10.7270/Q2VM4F0G
					More data for this Ligand-Target Pair