Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Histone deacetylase 1/2/3/4/5/6/7/8/9/11/Polyamine deacetylase HDAC10' and Ligand = 'BDBM50221735'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histone deacetylase 1/2/3/4/5/6/7/8/9/11/Polyamine deacetylase HDAC10 (Mus musculus-Mus musculus (Mouse))	BDBM50221735 (CHEMBL1790591) Show SMILES [H][C@@]12CCCCN1C(=O)[C@@]([H])(NC(=O)[C@@H](Cc1ccc(OC)cc1)NC(=O)[C@H](CCCCN(O)C(C)=O)NC2=O)[C@H](C)CC Show InChI InChI=1S/C30H45N5O7/c1-5-19(2)26-30(40)34-16-8-7-11-25(34)29(39)31-23(10-6-9-17-35(41)20(3)36)27(37)32-24(28(38)33-26)18-21-12-14-22(42-4)15-13-21/h12-15,19,23-26,41H,5-11,16-18H2,1-4H3,(H,31,39)(H,32,37)(H,33,38)/t19-,23+,24-,25+,26+/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	8.85E+4	n/a	n/a	n/a	n/a	n/a	n/a
Institute of Technology Curated by ChEMBL					Assay Description Inhibitory activity against histone deacetylases (HDAC) prepared from mouse melanoma B16/BL6 cells				Bioorg Med Chem Lett 14: 2427-31 (2004) Article DOI: 10.1016/j.bmcl.2004.03.018 BindingDB Entry DOI: 10.7270/Q20V8DC5
					More data for this Ligand-Target Pair