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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Histone deacetylase 1/2/3/4/5/6/7/8/9/11/Polyamine deacetylase HDAC10' and Ligand = 'BDBM50221741'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Histone deacetylase 1/2/3/4/5/6/7/8/9/11/Polyamine deacetylase HDAC10


(Mus musculus-Mus musculus (Mouse))		BDBM50221741
PNG
(CHEMBL1790588)
Show SMILES [H][C@]12CCCCN1C(=O)[C@@]([H])(NC(=O)[C@@H](Cc1ccc(OC)cc1)NC(=O)[C@H](CCCCCN(O)C(C)=O)NC2=O)[C@H](C)CC
Show InChI InChI=1S/C31H47N5O7/c1-5-20(2)27-31(41)35-17-10-8-12-26(35)30(40)32-24(11-7-6-9-18-36(42)21(3)37)28(38)33-25(29(39)34-27)19-22-13-15-23(43-4)16-14-22/h13-16,20,24-27,42H,5-12,17-19H2,1-4H3,(H,32,40)(H,33,38)(H,34,39)/t20-,24+,25-,26-,27+/m1/s1
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MMDB

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Article
PubMed
n/an/a 4.38E+4n/an/an/an/an/an/a



Institute of Technology

Curated by ChEMBL


Assay Description
Inhibitory activity against histone deacetylases (HDAC) prepared from mouse melanoma B16/BL6 cells

Bioorg Med Chem Lett 14: 2427-31 (2004)


Article DOI: 10.1016/j.bmcl.2004.03.018
BindingDB Entry DOI: 10.7270/Q20V8DC5
More data for this
Ligand-Target Pair