Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Histone deacetylase 1' and Ligand = 'BDBM375739'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histone deacetylase 1 (Homo sapiens (Human))	BDBM375739 (US10301323, Compound D4 | US9908899, Compound D4) Show SMILES Nc1ccccc1NC(=O)\C=C\c1cnn(Cc2ccccc2)c1 Show InChI InChI=1S/C19H18N4O/c20-17-8-4-5-9-18(17)22-19(24)11-10-16-12-21-23(14-16)13-15-6-2-1-3-7-15/h1-12,14H,13,20H2,(H,22,24)/b11-10+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer					Assay Description The HDAC activity inhibition assay was performed as follows to determine the ability of a test compound to inhibit HDAC enzymatic activity. Serial di...				J Med Chem 49: 1202-6 (2006) BindingDB Entry DOI: 10.7270/Q2JD504D
					More data for this Ligand-Target Pair
Histone deacetylase 1 (Homo sapiens (Human))	BDBM375739 (US10301323, Compound D4 | US9908899, Compound D4) Show SMILES Nc1ccccc1NC(=O)\C=C\c1cnn(Cc2ccccc2)c1 Show InChI InChI=1S/C19H18N4O/c20-17-8-4-5-9-18(17)22-19(24)11-10-16-12-21-23(14-16)13-15-6-2-1-3-7-15/h1-12,14H,13,20H2,(H,22,24)/b11-10+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
GSK					Assay Description The HDAC activity inhibition assay was performed as follows to determine the ability of a test compound to inhibit HDAC enzymatic activity. Serial di...				J Med Chem 50: 685-95 (2007) BindingDB Entry DOI: 10.7270/Q2736T75
					More data for this Ligand-Target Pair