Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Histone deacetylase 2' and Ligand = 'BDBM175097'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histone deacetylase 2 (Homo sapiens (Human))	BDBM175097 (US9115116, 6a) Show SMILES C[C@@H]1C[C@H](OC(=O)Nc2ccc(cc2)C#C)[C@@H]2[C@@H](CC[C@@H]3C[C@H](CC(=O)O3)O[Si](C)(C)C(C)(C)C)[C@@H](C)C=CC2=C1 |c:39,42| Show InChI InChI=1S/C34H47NO5Si/c1-9-24-11-14-26(15-12-24)35-33(37)39-30-19-22(2)18-25-13-10-23(3)29(32(25)30)17-16-27-20-28(21-31(36)38-27)40-41(7,8)34(4,5)6/h1,10-15,18,22-23,27-30,32H,16-17,19-21H2,2-8H3,(H,35,37)/t22-,23-,27+,28+,29-,30-,32-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	463	n/a	n/a	n/a	n/a	n/a	25
Academia Sinica; National Taiwan University US Patent					Assay Description The HDAC activity was performed using the HDAC fluorescent activity assay kit (BIOMOL, Plymouth Meeting, Pa., USA) according to the manufacturer'...				US Patent US9115116 (2015) BindingDB Entry DOI: 10.7270/Q2X34W7F
					More data for this Ligand-Target Pair