Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Histone deacetylase 2' and Ligand = 'BDBM483376'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histone deacetylase 2 (Homo sapiens (Human))	BDBM483376 (US10919902, Compound 120) Show SMILES Nc1ccc(nc1NC(=O)N1Cc2nccnc2C1)-c1ccc(F)cc1 Show InChI InChI=1S/C18H15FN6O/c19-12-3-1-11(2-4-12)14-6-5-13(20)17(23-14)24-18(26)25-9-15-16(10-25)22-8-7-21-15/h1-8H,9-10,20H2,(H,23,24,26)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	25	n/a	n/a	n/a	n/a	n/a
Alkermes, Inc. US Patent					Assay Description HDAC2 containing a C-terminal HIS-Tag (Proteros) and fluorescently-labeled anti-HIS-antibody are diluted in one vial in assay buffer 50 mM Tris, pH 8...				US Patent US10919902 (2021) BindingDB Entry DOI: 10.7270/Q26H4MHB
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