Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Histone deacetylase 3' and Ligand = 'BDBM24354'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histone deacetylase 3 (Homo sapiens (Human))	BDBM24354 (N-(4-{1-[(4-fluorophenyl)methyl]-1H-1,2,3-triazol-...) Show SMILES ONC(=O)CCCCCCC(=O)Nc1ccc(cc1)-c1cnnn1Cc1ccc(F)cc1 Show InChI InChI=1S/C23H26FN5O3/c24-19-11-7-17(8-12-19)16-29-21(15-25-28-29)18-9-13-20(14-10-18)26-22(30)5-3-1-2-4-6-23(31)27-32/h7-15,32H,1-6,16H2,(H,26,30)(H,27,31)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	16.4	n/a	n/a	n/a	n/a	n/a	n/a
University of Illinois at Chicago					Assay Description The inhibitory effects of compounds on histone deacetylase (HDAC) activity were determined using a fluorescence-based assay with electrophoretic sepa...				J Med Chem 51: 3437-48 (2008) Article DOI: 10.1021/jm701606b BindingDB Entry DOI: 10.7270/Q2ZC815S
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