Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Histone deacetylase 6' and Ligand = 'BDBM124205'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histone deacetylase 6 (Homo sapiens (Human))	BDBM124205 (US8748458, 11) Show SMILES COc1ccc(nc1)N(CCCCCCC(=O)NO)c1ccccn1 Show InChI InChI=1S/C18H24N4O3/c1-25-15-10-11-17(20-14-15)22(16-8-5-6-12-19-16)13-7-3-2-4-9-18(23)21-24/h5-6,8,10-12,14,24H,2-4,7,9,13H2,1H3,(H,21,23)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	13	n/a	n/a	n/a	n/a	n/a	37
Karus Therapeutics Limited US Patent					Assay Description In vitro HDAC assays were performed using a HDAC fluorescent activity assay kit (Biomol, UK) according to the manufacturer's instructions. Compounds ...				US Patent US8748458 (2014) BindingDB Entry DOI: 10.7270/Q22N50Z7
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