Compile Data Set for Download or QSAR

Found 5 hits Enz. Inhib. hit(s) with Target = 'Histone deacetylase 6' and Ligand = 'BDBM218202'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histone deacetylase 6 (Homo sapiens (Human))	BDBM218202 (US9249087, 43) Show SMILES ONC(=O)c1ccc(Cn2cccn2)cc1 Show InChI InChI=1S/C11H11N3O2/c15-11(13-16)10-4-2-9(3-5-10)8-14-7-1-6-12-14/h1-7,16H,8H2,(H,13,15)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	10.9	n/a	n/a	n/a	n/a	8.0	n/a
THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS; THE CHILDREN'S HOSPITAL OF PHILADELPHIA US Patent					Assay Description HDAC assay is performed using fluorescently-labeled acetylated substrate, which comprises an acetylated lysine side chain. After incubation with HDAC...				US Patent US9249087 (2016) BindingDB Entry DOI: 10.7270/Q2Q23Z3W
					More data for this Ligand-Target Pair
Histone deacetylase 6 (Mus musculus)	BDBM218202 (US9249087, 43) Show SMILES ONC(=O)c1ccc(Cn2cccn2)cc1 Show InChI InChI=1S/C11H11N3O2/c15-11(13-16)10-4-2-9(3-5-10)8-14-7-1-6-12-14/h1-7,16H,8H2,(H,13,15)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	46	n/a	n/a	n/a	n/a	n/a	n/a
University of Illinois at Chicago Curated by ChEMBL					Assay Description Inhibition of HDAC6 in mouse N2A cells				ACS Med Chem Lett 11: 706-712 (2020) Article DOI: 10.1021/acsmedchemlett.9b00560 BindingDB Entry DOI: 10.7270/Q2KH0RVC
					More data for this Ligand-Target Pair
Histone deacetylase 6 (Homo sapiens (Human))	BDBM218202 (US9249087, 43) Show SMILES ONC(=O)c1ccc(Cn2cccn2)cc1 Show InChI InChI=1S/C11H11N3O2/c15-11(13-16)10-4-2-9(3-5-10)8-14-7-1-6-12-14/h1-7,16H,8H2,(H,13,15)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	102	n/a	n/a	n/a	n/a	n/a	n/a
Preclinical R&D Curated by ChEMBL					Assay Description Inhibition of recombinant full length human N-terminal GST-tagged HDAC6 expressed in baculovirus infected sf9 insect cells pretreated with compound f...				J Med Chem 62: 10711-10739 (2019) Article DOI: 10.1021/acs.jmedchem.9b01194 BindingDB Entry DOI: 10.7270/Q2KP85MZ
					More data for this Ligand-Target Pair
Histone deacetylase 6 (Homo sapiens (Human))	BDBM218202 (US9249087, 43) Show SMILES ONC(=O)c1ccc(Cn2cccn2)cc1 Show InChI InChI=1S/C11H11N3O2/c15-11(13-16)10-4-2-9(3-5-10)8-14-7-1-6-12-14/h1-7,16H,8H2,(H,13,15)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	102	n/a	n/a	n/a	n/a	n/a	n/a
Preclinical R&D Curated by ChEMBL					Assay Description Inhibition of recombinant full length human N-terminal GST-tagged HDAC6 expressed in baculovirus infected sf9 insect cells pretreated with compound f...				J Med Chem 62: 10711-10739 (2019) Article DOI: 10.1021/acs.jmedchem.9b01194 BindingDB Entry DOI: 10.7270/Q2KP85MZ
					More data for this Ligand-Target Pair
Histone deacetylase 6 (Mus musculus)	BDBM218202 (US9249087, 43) Show SMILES ONC(=O)c1ccc(Cn2cccn2)cc1 Show InChI InChI=1S/C11H11N3O2/c15-11(13-16)10-4-2-9(3-5-10)8-14-7-1-6-12-14/h1-7,16H,8H2,(H,13,15)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	932	n/a	n/a	n/a	n/a
University of Illinois at Chicago Curated by ChEMBL					Assay Description Inhibition of HDAC6 in mouse N2A cells assessed as increase in alpha tubulin acetylation				ACS Med Chem Lett 11: 706-712 (2020) Article DOI: 10.1021/acsmedchemlett.9b00560 BindingDB Entry DOI: 10.7270/Q2KH0RVC
					More data for this Ligand-Target Pair