Compile Data Set for Download or QSAR

Found 3 hits Enz. Inhib. hit(s) with Target = 'Histone deacetylase 6' and Ligand = 'BDBM337657'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histone deacetylase 6 (Homo sapiens (Human))	BDBM337657 (US10227295, Compound 9a | US9751832, Compound 9a |...) Show SMILES OCc1ccc(NC(=O)NCc2ccc(cc2)C(=O)NO)cc1 Show InChI InChI=1S/C16H17N3O4/c20-10-12-3-7-14(8-4-12)18-16(22)17-9-11-1-5-13(6-2-11)15(21)19-23/h1-8,20,23H,9-10H2,(H,19,21)(H2,17,18,22)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	8.30	n/a	n/a	n/a	n/a	n/a	n/a
H. Lee Moffitt Cancer Center and Research Institute, Inc.; Board of Trustees of the University of Illinois US Patent					Assay Description HDAC inhibition assays were performed by Reaction Biology Corp. (Malvern, Pa.) using isolated human, recombinant full-length HDAC1 and -6 from a bacu...				US Patent US9751832 (2017) BindingDB Entry DOI: 10.7270/Q23T9KBR
					More data for this Ligand-Target Pair
Histone deacetylase 6 (Homo sapiens (Human))	BDBM337657 (US10227295, Compound 9a | US9751832, Compound 9a |...) Show SMILES OCc1ccc(NC(=O)NCc2ccc(cc2)C(=O)NO)cc1 Show InChI InChI=1S/C16H17N3O4/c20-10-12-3-7-14(8-4-12)18-16(22)17-9-11-1-5-13(6-2-11)15(21)19-23/h1-8,20,23H,9-10H2,(H,19,21)(H2,17,18,22)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	8.30	n/a	n/a	n/a	n/a	n/a	n/a
KuDOS Pharmaceuticals Ltd.					Assay Description HDAC inhibition assays were performed by Reaction Biology Corp. (Malvern, Pa.) using isolated human, recombinant full-length HDAC1 and -6 from a bacu...				J Med Chem 51: 6581-91 (2008) BindingDB Entry DOI: 10.7270/Q2BZ68CW
					More data for this Ligand-Target Pair
Histone deacetylase 6 (Homo sapiens (Human))	BDBM337657 (US10227295, Compound 9a | US9751832, Compound 9a |...) Show SMILES OCc1ccc(NC(=O)NCc2ccc(cc2)C(=O)NO)cc1 Show InChI InChI=1S/C16H17N3O4/c20-10-12-3-7-14(8-4-12)18-16(22)17-9-11-1-5-13(6-2-11)15(21)19-23/h1-8,20,23H,9-10H2,(H,19,21)(H2,17,18,22)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	8.30	n/a	n/a	n/a	n/a	n/a	n/a
Vernalis (R&D) Ltd					Assay Description HDAC inhibition assays were performed by Reaction Biology Corp. (Malvern, Pa.) using isolated human, recombinant full-length HDAC1 and -6 from a bacu...				J Med Chem 51: 196-218 (2008) BindingDB Entry DOI: 10.7270/Q2VD71RF
					More data for this Ligand-Target Pair