Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Histone deacetylase 6 [440-798] (Danio rerio) | BDBM19149 (CHEMBL98 | N-hydroxy-N'-phenyloctanediamide | SAHA...) | PDB UniProtKB/TrEMBL GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | 0.600 | -52.6 | 1.10 | n/a | n/a | n/a | n/a | n/a | 25 |
University of Pennsylvania, | Assay Description The fluorescence anisotropy assay was performed with fluorescein-labeled SAHA (fl-SAHA, gift of C. Fierke, University of Michigan) and measured using... | Nat Chem Biol 12: 741-747 (2016) Article DOI: 10.1038/nchembio.2134 BindingDB Entry DOI: 10.7270/Q2TH8KH1 | |||||||||||
More data for this Ligand-Target Pair |