Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Histone deacetylase 8' and Ligand = 'BDBM120959'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histone deacetylase 8 (Homo sapiens (Human))	BDBM120959 (US8716285, 16) Show SMILES CN(C)c1cccc(c1)-c1ccnc(NC2CCc3ccc(cc3C2)C(=O)NO)n1 Show InChI InChI=1S/C23H25N5O2/c1-28(2)20-5-3-4-16(14-20)21-10-11-24-23(26-21)25-19-9-8-15-6-7-17(22(29)27-30)12-18(15)13-19/h3-7,10-12,14,19,30H,8-9,13H2,1-2H3,(H,27,29)(H,24,25,26)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	800	n/a	n/a	n/a	n/a	n/a	n/a
Hoffmann-La Roche Inc. US Patent					Assay Description Compounds were tested for their ability to inhibit histone deacetylase 8 using an in vitro deacetylation assay. In a detailed procedure, 8 μl o...				US Patent US8716285 (2014) BindingDB Entry DOI: 10.7270/Q2K072XG
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