Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Histone deacetylase 8' and Ligand = 'BDBM50138412'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histone deacetylase 8 (Homo sapiens (Human))	BDBM50138412 (2-[5-(Formyl-hydroxy-amino)-pentyl]-N,N'-di-quinol...) Show SMILES ON(CCCCCC(C(=O)Nc1cnc2ccccc2c1)C(=O)Nc1cnc2ccccc2c1)C=O Show InChI InChI=1S/C27H27N5O4/c33-18-32(36)13-7-1-2-10-23(26(34)30-21-14-19-8-3-5-11-24(19)28-16-21)27(35)31-22-15-20-9-4-6-12-25(20)29-17-22/h3-6,8-9,11-12,14-18,23,36H,1-2,7,10,13H2,(H,30,34)(H,31,35)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	690	n/a	n/a	n/a	n/a	n/a	n/a
The Scripps Research Institute Curated by ChEMBL					Assay Description Inhibition of Histone deacetylase 8 (HDAC8) of HeLa nuclear extracts				Bioorg Med Chem Lett 14: 449-53 (2003) BindingDB Entry DOI: 10.7270/Q2HH6JH2
					More data for this Ligand-Target Pair