Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Histone deacetylase 8' and Ligand = 'BDBM50302062'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histone deacetylase 8 (Homo sapiens (Human))	BDBM50302062 (6-((5S,8S,11S)-11-((1H-indol-3-yl)methyl)-2,2-dime...) Show SMILES CC1(C)NC(=O)C[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2cccc3ccccc23)NC(=O)[C@H](CCCCCC(O)=O)NC1=O |r| Show InChI InChI=1S/C37H43N5O6/c1-37(2)36(48)41-30(17-4-3-5-18-33(44)45)34(46)40-31(20-24-13-10-12-23-11-6-7-14-27(23)24)35(47)39-26(21-32(43)42-37)19-25-22-38-29-16-9-8-15-28(25)29/h6-16,22,26,30-31,38H,3-5,17-21H2,1-2H3,(H,39,47)(H,40,46)(H,41,48)(H,42,43)(H,44,45)/t26-,30-,31-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.67E+3	n/a	n/a	n/a	n/a	n/a	n/a
The Scripps Research Institute Curated by ChEMBL					Assay Description Inhibition of human recombinant HDAC8 after 30 mins by fluorimetric assay				J Med Chem 52: 7836-46 (2009) Article DOI: 10.1021/jm900850t BindingDB Entry DOI: 10.7270/Q2M046DK
					More data for this Ligand-Target Pair