Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Histone deacetylase 8' and Ligand = 'BDBM50356636'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histone deacetylase 8 (Homo sapiens (Human))	BDBM50356636 (CHEMBL1914701) Show SMILES ONC(=O)CCCCCCNC(=O)c1cc(on1)-c1ccc(cc1)N=[N+]=[N-] Show InChI InChI=1S/C17H20N6O4/c18-23-20-13-8-6-12(7-9-13)15-11-14(22-27-15)17(25)19-10-4-2-1-3-5-16(24)21-26/h6-9,11,26H,1-5,10H2,(H,19,25)(H,21,24)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	707	n/a	n/a	n/a	n/a	n/a	n/a
University of Illinois at Chicago Curated by ChEMBL					Assay Description Inhibition of human recombinant HDAC8 using Fluor de Lys as substrate				J Med Chem 54: 4350-64 (2011) Article DOI: 10.1021/jm2001025 BindingDB Entry DOI: 10.7270/Q2RX9CG0
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