Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Histone deacetylase 8' and Ligand = 'BDBM50538988'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histone deacetylase 8 (Homo sapiens (Human))	BDBM50538988 (CHEMBL4638018) Show SMILES ONC(=O)CCCCCONC(=O)c1cc(cc(c1)C(F)(F)F)C(F)(F)F Show InChI InChI=1S/C15H16F6N2O4/c16-14(17,18)10-6-9(7-11(8-10)15(19,20)21)13(25)23-27-5-3-1-2-4-12(24)22-26/h6-8,26H,1-5H2,(H,22,24)(H,23,25)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	4.90E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Heinrich-Heine-Universit£t D£sseldorf Curated by ChEMBL					Assay Description Inhibition of recombinant human HDAC8				Bioorg Med Chem 28: (2020) Article DOI: 10.1016/j.bmc.2019.115108 BindingDB Entry DOI: 10.7270/Q2NV9NSQ
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