Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Histone deacetylase 8' and Ligand = 'BDBM50541221'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histone deacetylase 8 (Homo sapiens (Human))	BDBM50541221 (CHEMBL4633689) Show SMILES Cl.C[C@H](NC(=O)[C@H](N)Cc1ccc(Cl)cc1Cl)c1ccccc1 |r| Show InChI InChI=1S/C17H18Cl2N2O.ClH/c1-11(12-5-3-2-4-6-12)21-17(22)16(20)9-13-7-8-14(18)10-15(13)19;/h2-8,10-11,16H,9,20H2,1H3,(H,21,22);1H/t11-,16+;/m0./s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	7.64E+4	n/a	n/a	n/a	n/a	n/a	n/a
University College London Curated by ChEMBL					Assay Description Inhibition of HDAC8 (unknown origin)				Bioorg Med Chem Lett 30: (2020) Article DOI: 10.1016/j.bmcl.2019.126926 BindingDB Entry DOI: 10.7270/Q2542S35
					More data for this Ligand-Target Pair