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Found 1 hit Enz. Inhib. hit(s) with Target = 'Histone lysine demethylase PHF8' and Ligand = 'BDBM276061'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Histone lysine demethylase PHF8


(Homo sapiens (Human))		BDBM276061
PNG
(2-[1-(2-naphthalen-1-ylethyl)imidazol-4-yl]-4-(1H-...)
Show SMILES C(Cn1cnc(c1)-c1cc(ccn1)-c1c[nH]nn1)c1cccc2ccccc12
Show InChI InChI=1S/C22H18N6/c1-2-7-19-16(4-1)5-3-6-17(19)9-11-28-14-22(24-15-28)20-12-18(8-10-23-20)21-13-25-27-26-21/h1-8,10,12-15H,9,11H2,(H,25,26,27)
PDB

UniProtKB/SwissProt

antibodypedia
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PC cid
PC sid
UniChem
US Patent
n/an/a 300n/an/an/an/an/an/a



GSK



Assay Description
PHF8 Assay: The ability of test compounds to inhibit the activity of PHF8 was determined in 384-well plate format under the following reaction condit...

Bioorg Med Chem Lett 17: 1584-9 (2007)


BindingDB Entry DOI: 10.7270/Q2FT8PBQ
More data for this
Ligand-Target Pair