Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Histone-lysine N-methyltransferase EZH2 (Homo sapiens (Human)) | BDBM326127 (US10273223, Compound D-25 | US9637472, Compound D-...) | PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | <300 | n/a | n/a | n/a | n/a | n/a | n/a |
IRBM/Merck | Assay Description eneral Procedure for Wild-Type PRC2 Enzyme Assay on Oligonucleosome Substrate. The assays was performed in a buffer consisting of 20 mM bicine (pH=7.... | J Med Chem 51: 2350-3 (2008) BindingDB Entry DOI: 10.7270/Q28P62V9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Histone-lysine N-methyltransferase EZH2 (Homo sapiens (Human)) | BDBM326127 (US10273223, Compound D-25 | US9637472, Compound D-...) | PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | <300 | n/a | n/a | n/a | n/a | n/a | n/a |
Epizyme, Inc. US Patent | Assay Description Recombinant PRC2 Enzymes. Human PRC2 enzymes were purified as 4-component enzyme complexes co-expressed in Spodoptera frugiperda (sf9) cells using a ... | US Patent US9637472 (2017) BindingDB Entry DOI: 10.7270/Q2X0693B | |||||||||||
More data for this Ligand-Target Pair |