Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Histone-lysine N-methyltransferase EZH2' and Ligand = 'BDBM50010824'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histone-lysine N-methyltransferase EZH2 (Homo sapiens (Human))	BDBM50010824 (CHEMBL3264788) Show SMILES CC1(C)CC(CC(C)(C)N1)NC(=O)c1ccc(Oc2cccc(-c3ccncn3)c2C#N)c(Cl)c1 Show InChI InChI=1S/C27H28ClN5O2/c1-26(2)13-18(14-27(3,4)33-26)32-25(34)17-8-9-24(21(28)12-17)35-23-7-5-6-19(20(23)15-29)22-10-11-30-16-31-22/h5-12,16,18,33H,13-14H2,1-4H3,(H,32,34)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	24	n/a	n/a	n/a	n/a	n/a	n/a
Constellation Pharmaceuticals Curated by ChEMBL					Assay Description Inhibition of wild type EZH2 (unknown origin)				ACS Med Chem Lett 5: 378-83 (2014) Article DOI: 10.1021/ml400494b BindingDB Entry DOI: 10.7270/Q2BP04BR
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