Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Histone-lysine N-methyltransferase EZH2' and Ligand = 'BDBM50010825'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histone-lysine N-methyltransferase EZH2 (Homo sapiens (Human))	BDBM50010825 (CHEMBL3264789) Show SMILES CC1(C)CC(CC(C)(C)N1CCO)NC(=O)c1ccc(Oc2ccccc2C#N)c(Cl)c1 Show InChI InChI=1S/C25H30ClN3O3/c1-24(2)14-19(15-25(3,4)29(24)11-12-30)28-23(31)17-9-10-22(20(26)13-17)32-21-8-6-5-7-18(21)16-27/h5-10,13,19,30H,11-12,14-15H2,1-4H3,(H,28,31)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
Constellation Pharmaceuticals Curated by ChEMBL					Assay Description Inhibition of wild type EZH2 (unknown origin)				ACS Med Chem Lett 5: 378-83 (2014) Article DOI: 10.1021/ml400494b BindingDB Entry DOI: 10.7270/Q2BP04BR
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