Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Histone-lysine N-methyltransferase EZH2 (Homo sapiens (Human)) | BDBM50562994 (CHEMBL4740532) | PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 2 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of wild type EZH2 (unknown origin) | Citation and Details Article DOI: 10.1021/acs.jmedchem.0c02112 BindingDB Entry DOI: 10.7270/Q23J3HPC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Histone-lysine N-methyltransferase EZH2 (Homo sapiens (Human)) | BDBM50562994 (CHEMBL4740532) | PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 7 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of wild type EZH2 Y641N mutant (unknown origin) | Citation and Details Article DOI: 10.1021/acs.jmedchem.0c02112 BindingDB Entry DOI: 10.7270/Q23J3HPC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Histone-lysine N-methyltransferase EZH2 (Homo sapiens (Human)) | BDBM50562994 (CHEMBL4740532) | PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 30 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of wild type EZH2 in human KARPAS-422 cells assessed as effect on H3K27Me3 levels | Citation and Details Article DOI: 10.1021/acs.jmedchem.0c02112 BindingDB Entry DOI: 10.7270/Q23J3HPC | |||||||||||
More data for this Ligand-Target Pair |