Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Histone-lysine N-methyltransferase SMYD3' and Ligand = 'BDBM433087'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histone-lysine N-methyltransferase SMYD3 (Homo sapiens (Human))	BDBM433087 (5-cyclopropyl-N-((1R,3r,5S)-8-((4- (phenethylamino...) Show SMILES O=C(N[C@@H]1C[C@@H]2CC[C@H](C1)N2S(=O)(=O)N1CCC(CC1)NCCc1ccccc1)c1cc(on1)C1CC1 |r,TLB:11:10:7.6:4.3.9| Show InChI InChI=1S/C27H37N5O4S/c33-27(25-18-26(36-30-25)20-6-7-20)29-22-16-23-8-9-24(17-22)32(23)37(34,35)31-14-11-21(12-15-31)28-13-10-19-4-2-1-3-5-19/h1-5,18,20-24,28H,6-17H2,(H,29,33)/t22-,23+,24-	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.82	n/a	n/a	n/a	n/a	n/a	n/a
EPIZYME, INC. US Patent					Assay Description The assays were all performed in a buffer consisting of 25 mM Tris-Cl pH 8.0, 1 mM TCEP, 0.005% BSG, and 0.005% Tween 20, prepared on the day of use....				US Patent US10577363 (2020) BindingDB Entry DOI: 10.7270/Q2BZ68G7
					More data for this Ligand-Target Pair