Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Histone-lysine N-methyltransferase SMYD3' and Ligand = 'BDBM433091'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histone-lysine N-methyltransferase SMYD3 (Homo sapiens (Human))	BDBM433091 (5-cyclopropyl-N-((2S,4S)-2-methyl-1-((2- ((S)-1-me...) Show SMILES C[C@H]1C[C@H](CCN1S(=O)(=O)CC[C@@H]1CCN(C)C1)NC(=O)c1cc(on1)C1CC1 |r| Show InChI InChI=1S/C20H32N4O4S/c1-14-11-17(21-20(25)18-12-19(28-22-18)16-3-4-16)6-9-24(14)29(26,27)10-7-15-5-8-23(2)13-15/h12,14-17H,3-11,13H2,1-2H3,(H,21,25)/t14-,15-,17-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.87	n/a	n/a	n/a	n/a	n/a	n/a
EPIZYME, INC. US Patent					Assay Description The assays were all performed in a buffer consisting of 25 mM Tris-Cl pH 8.0, 1 mM TCEP, 0.005% BSG, and 0.005% Tween 20, prepared on the day of use....				US Patent US10577363 (2020) BindingDB Entry DOI: 10.7270/Q2BZ68G7
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