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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Hormone-sensitive lipase' and Ligand = 'BDBM50233404'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Hormone-sensitive lipase


(Homo sapiens (Human))		BDBM50233404
PNG
(CHEMBL4085350)
Show SMILES CC1(C)OB(OC1(C)C)c1ccccc1NC(=O)c1ccc(Oc2ccc(cn2)C(F)(F)F)cn1
Show InChI InChI=1S/C24H23BF3N3O4/c1-22(2)23(3,4)35-25(34-22)17-7-5-6-8-18(17)31-21(32)19-11-10-16(14-29-19)33-20-12-9-15(13-30-20)24(26,27)28/h5-14H,1-4H3,(H,31,32)
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n/an/a 920n/an/an/an/an/an/a



Daiichi Sankyo Co., Ltd.

Curated by ChEMBL


Assay Description
Inhibition of recombinant human HSL expressed in baculovirus infected sf9 cells using PNPB as substrate after 5 mins by spectrophotometric method

Bioorg Med Chem 25: 2234-2243 (2017)


Article DOI: 10.1016/j.bmc.2017.02.045
BindingDB Entry DOI: 10.7270/Q2VH5R3W
More data for this
Ligand-Target Pair