Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Hormone-sensitive lipase' and Ligand = 'BDBM97634'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Hormone-sensitive lipase (Homo sapiens (Human))	BDBM97634 (US8470843, 10) Show SMILES CC(Oc1ccc(cc1)N1CCC2(CCN(CC2O)S(=O)(=O)c2ccccc2Cl)C1=O)C(F)(F)F Show InChI InChI=1S/C23H24ClF3N2O5S/c1-15(23(25,26)27)34-17-8-6-16(7-9-17)29-13-11-22(21(29)31)10-12-28(14-20(22)30)35(32,33)19-5-3-2-4-18(19)24/h2-9,15,20,30H,10-14H2,1H3	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	20	n/a	n/a	n/a	n/a	7.2	4
Hoffmann-La Roche Inc. US Patent					Assay Description HSL enzyme activity was measured by a colorimetric assay using 2,3-dimercapto-1-propanol tributyrate (Aldrich, St. Louis, MO) as a substrate.				US Patent US8470843 (2013) BindingDB Entry DOI: 10.7270/Q2WH2NMJ
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