BindingDB logo
myBDB logout
Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Hydroxycarboxylic acid receptor 1' and Ligand = 'BDBM50539680'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Hydroxycarboxylic acid receptor 1


(Homo sapiens (Human))		BDBM50539680
PNG
(CHEMBL4643496)
Show SMILES CCOc1cc(Cl)c(cc1N1CCOCC1)C(=O)NC(=O)Nc1nc2CCN(Cc2s1)C(=O)CO
Show InChI InChI=1S/C22H26ClN5O6S/c1-2-34-17-10-14(23)13(9-16(17)27-5-7-33-8-6-27)20(31)25-21(32)26-22-24-15-3-4-28(19(30)12-29)11-18(15)35-22/h9-10,29H,2-8,11-12H2,1H3,(H2,24,25,26,31,32)
Reactome pathway
KEGG

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/an/an/a 895n/an/an/an/a



AstraZeneca

Curated by ChEMBL


Assay Description
Agonist activity at human GPR81 overexpressed in CHO cells assessed as inhibition of forskolin-stimulated cAMP production

Bioorg Med Chem Lett 30: (2020)


Article DOI: 10.1016/j.bmcl.2020.126953
BindingDB Entry DOI: 10.7270/Q2125X5X
More data for this
Ligand-Target Pair