Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Hypoxia-inducible factor 1-alpha' and Ligand = 'BDBM50354116'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Hypoxia-inducible factor 1-alpha (Homo sapiens (Human))	BDBM50354116 (CHEMBL1836235) Show SMILES CCOC(=O)N1CCN(Cc2nc3ccccc3c(=O)n2-c2ccccc2OCC)CC1 |(-1.33,-7.32,;,-6.55,;,-5.01,;1.33,-4.24,;2.67,-5.01,;1.33,-2.7,;2.67,-1.93,;2.67,-.39,;1.33,.38,;1.33,1.92,;,2.69,;-1.33,1.92,;-2.67,2.69,;-4,1.92,;-5.33,2.69,;-5.33,4.23,;-4,5,;-2.67,4.23,;-1.33,5,;-1.33,6.54,;,4.23,;1.33,5.01,;1.33,6.55,;2.67,7.32,;4,6.54,;4,5,;2.67,4.23,;2.67,2.69,;4,1.92,;5.33,2.69,;,-.38,;,-1.93,)| Show InChI InChI=1S/C24H28N4O4/c1-3-31-21-12-8-7-11-20(21)28-22(25-19-10-6-5-9-18(19)23(28)29)17-26-13-15-27(16-14-26)24(30)32-4-2/h5-12H,3-4,13-17H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	9.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
National Human Genome Research Institute Curated by ChEMBL					Assay Description Inhibition of hypoxia-induced HIF1alpha activation in human ME180 cells by HRE3-Bla-luciferase reporter gene assay				Bioorg Med Chem Lett 21: 5239-43 (2011) Article DOI: 10.1016/j.bmcl.2011.07.043 BindingDB Entry DOI: 10.7270/Q2H70G65
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