Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Hypoxia-inducible factor 1-alpha' and Ligand = 'BDBM50354122'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Hypoxia-inducible factor 1-alpha (Homo sapiens (Human))	BDBM50354122 (CHEMBL1836230) Show SMILES CCOc1ccccc1-n1c(CN2CCN(CC2)C(=O)c2ccco2)nc2cccc(C)c2c1=O |(5.33,2.47,;4,1.7,;2.67,2.47,;2.67,4.01,;4,4.78,;4,6.32,;2.67,7.09,;1.33,6.32,;1.33,4.78,;,4.01,;,2.47,;1.33,1.7,;1.33,.16,;,-.61,;,-2.15,;1.33,-2.92,;2.67,-2.15,;2.67,-.61,;1.33,-4.46,;2.67,-5.23,;,-5.23,;-1.41,-4.61,;-2.44,-5.75,;-1.67,-7.09,;-.16,-6.77,;-1.33,1.7,;-2.67,2.47,;-4,1.7,;-5.33,2.47,;-5.33,4.01,;-4,4.78,;-4,6.32,;-2.67,4.01,;-1.33,4.78,;-1.33,6.32,)| Show InChI InChI=1S/C27H28N4O4/c1-3-34-22-11-5-4-10-21(22)31-24(28-20-9-6-8-19(2)25(20)27(31)33)18-29-13-15-30(16-14-29)26(32)23-12-7-17-35-23/h4-12,17H,3,13-16,18H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
National Human Genome Research Institute Curated by ChEMBL					Assay Description Inhibition of hypoxia-induced HIF1alpha activation in human ME180 cells by HRE3-Bla-luciferase reporter gene assay				Bioorg Med Chem Lett 21: 5239-43 (2011) Article DOI: 10.1016/j.bmcl.2011.07.043 BindingDB Entry DOI: 10.7270/Q2H70G65
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